hemoglobinurias การใช้

• It is the first approved therapy for paroxysmal nocturnal hemoglobinuria.
• Paroxysmal cold hemoglobinuria is treated by removing the underlying cause, such as infection.
• It was initially approved to treat paroxysmal nocturnal hemoglobinuria, a rare blood disorder.
• Red cell destruction in these acute hemolytic events is largely intravascular and therefore is associated with hemoglobinuria.
• Hemoglobinuria is seen due to excretion of red-blood-cell lysis byproducts via the kidneys.
• It is possible to use an ammonia sulphate precipitation test in order to distinguish between hemoglobinuria and myoglobinuria.
• The symptoms are fever and chills, sometimes with back pain and pink or red urine ( hemoglobinuria ).
• Most notably, deficiency of the MAC inhibitor CD59 results in an overactivity of complement and Paroxysmal nocturnal hemoglobinuria.
• :: : : The most dramatic disease which causes the symptoms you describe, is Paroxysmal cold hemoglobinuria.
• Sir Dacie is credited with characterizing the relationship between paroxysmal nocturnal hemoglobinuria and bone marrow failure syndromes like aplastic anemia.
• Splenomegaly, severe headache, hepatomegaly ( enlarged liver ), hypoglycemia, and hemoglobinuria with renal failure may occur.
• In animals, babesiosis is suspected by observation of clinical signs ( hemoglobinuria and anemia ) in animals in endemic areas.
• Castle and his team later characterized the red blood cell defects that are responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis.
• Two colour charts are provided that correspond to the reactions that occur with hemoglobinuria, myoglobinuria and hematuria ( RBCs ).
• Mutations affecting GPI that reduce expression of CD59 and decay-accelerating factor on red blood cells result in paroxysmal nocturnal hemoglobinuria.
• In 1931, he described Paroxysmal nocturnal hemoglobinuria in depth, and also a rare form of this disease Str黚ing-Marchiafava-Micheli Syndrome.
• To formally diagnose agranulocytosis, other pathologies with a similar presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias.
• Disorders of the proteins in these membranes are associated with many disorders, such as hereditary spherocytosis, hereditary elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria.
• Although diamphotoxin has no neurotoxic effect, its hemolytic effect is lethal, and may reduce hemoglobin levels by as much as 75 %, leading to hemoglobinuria.
• Hemoglobinuria can be caused by hemolytic anaemia, blood transfusions, extensive burns, the bite of the recluse spider ( Loxosceles ), infections and strenuous exercise.