hypercalciuria การใช้

• It is also sometimes used for treatment of hypoparathyroidism, hypercalciuria, Dent's disease, and M閚i鑢e's disease.
• Overall, it was noted that the drug could be used to correct the increased calcium absorption that occurs in absorptive hypercalciuria.
• The mechanisms by which CLC-5 dysfunction results in hypercalciuria and the other features of Dent's disease remain to be elucidated.
• Rabbits are prone to hypercalciuria due to intestinal absorption of calcium not being dependent on vitamin D and a high fractional urinary excretion of calcium.
• Another inherited disease that affects the kidney organs is Dent's Disease, characterised by low molecular weight proteinuria and hypercalciuria where mutations in CLCN5 are implicated.
• Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure.
• However, Bartter syndrome is also characterized by high renin, high aldosterone, hypercalciuria, and an abnormal Na +-K +-2Cl  " transporter in the thick ascending limb of the loop of Henle, Gitelman syndrome causes hypocalciuria and is due to an abnormal thiazide transporter in the distal segment.