hypercholesterolaemia การใช้

• There are several international guidelines on the treatment of hypercholesterolaemia.
• Colestilan was also investigated in phase III trials in Europe and Asia for hypercholesterolaemia.
• High levels are seen in type II hypercholesterolaemia, hypertriglyceridemia, and in the nephrotic syndrome.
• Obesity and diabetes mellitus are often linked to cardiovascular disease, as are a history of chronic kidney disease and hypercholesterolaemia.
• He championed cascade testing for familial hypercholesterolaemia with the British Heart Foundation so that Wales became the first UK country to introduce it successfully.
• Artichoke leaf extract has been investigated for its potential to lower cholesterol levels for people with hypercholesterolaemia, but no convincing medical evidence indicates it is effective.
• Frameshift mutations are apparent in severe genetic diseases such as Tay-Sachs disease; they increase susceptibility to certain cancers and classes of familial hypercholesterolaemia; in 1997, a frameshift mutation was linked to resistance to infection by the HIV retrovirus.
• Many market ( store-bought ) foods are high in fats, carbohydrates, and sodium; and these may lead to increased weight gain, high cholesterol ( hypercholesterolaemia ), high blood pressure ( hypertension ), and chronic diseases.
• He has created and led large studies that transformed statins from esoteric drugs for familial hypercholesterolaemia into widely used placebo-controlled trials and worldwide Cholesterol Treatment Trialists meta-analyses confirmed heart attack reduction, discovered stroke reduction, and demonstrated safety and efficacy in many different types of patient.
• Endothelial dysfunction can result from and / or contribute to several disease processes, as occurs in hypertension, hypercholesterolaemia, diabetes, septic shock, and Behcet's disease, and it can also result from environmental factors, such as from smoking tobacco products and exposure to air pollution.
• A 2007 meta-analysis found that " the proposed strategy of screening children and parents for familial hypercholesterolaemia could have considerable impact in preventing the medical consequences of this disorder in two generations simultaneously . " " The use of total cholesterol alone may best discriminate between people with and without FH between the ages of 1 to 9 years ."
• Meanwhile, a lab led by Catherine Boileau at the Necker-Enfants Malades Hospital in Paris had been following families with familial hypercholesterolaemia, a genetic condition that, in 90 % of cases causes coronary artery disease ( FRAMINGHAM study ) and in 60 % of cases may lead to an early death; they had identified a mutation on chromosome 1 carried by some of these families, but had been unable to identify the relevant gene.