hypericin การใช้

• Anthracyclines, hypericin and phenolic lipids are derived from polyketides cyclisation.
• Hypericin and pseudohypericin have shown both antiviral and antibacterial activities.
• Two main compounds of interest have been studied in more detail : hyperforin and hypericin.
• Such compounds include : oligomeric procyanidines, flavonoids ( quercetin ), hypericin, and pseudohypericin.
• But, he explained, " hypericin is not directly linked to its antidepressant activity ."
• Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells.
• He estimates 60 to 80 percent of people get relief with formulations that contain about 0.3 percent hypericin.
• The naphthodianthrones hypericin and pseudohypericin along with the phloroglucinol derivative hyperforin are thought to be among the numerous active constituents.
• It was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme.
• The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.
• Photosensitizations are classified as primary if an ingested plant contains a photosensitive substance, like hypericin in buckwheat plants ( green or dried ) in horses.
• For that reason, " therapeutic grade " hypericum, which usually comes as 300-milligram capsules ( 0.3 percent hypericin ), is most recommended.
• St . John's wort, for example, recently made headlines when laboratory testing found competing brands often don't contain levels of the active ingredient hypericin promised on the bottle.
• The crude extract of " Hypericum " is a weak inhibitor of MAO-B . Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors.
• For years, researchers assumed that the key active ingredients are hypericin and pseudohypericin, but these chemicals do not seem to cross the blood-brain barrier, a membrane that protects the brain.
• If a capsule is chosen, look for brands containing 300 milligrams of the raw herb, standardized to contain 0.3 percent hypericin, one of the herb's most active ingredients.
• Hyperforin ( along with adhyperforin ) is believed to be one of the three chief active constituents of St . John's wort-the other two being hypericin ( along with pseudohypericin ) and several flavonoid constituents.
• In the case of hypericum, that appears to be true : the plant contains hypericin, an antidepressant compound; flavonoids, which boost the immune system; and chemicals that may reduce inflammation and combat viruses and bacteria.
• In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes.
• In phytopharmaceutical or herbal medicine, the active ingredient may be either unknown or may require St John's wort is often standardized to the hypericin which is now known not to be the " active ingredient " for antidepressant use.