hypervariable การใช้

• This region is known as the " hypervariable region ".
• There are two mitochondrial hypervariable regions used in human mitochondrial genealogical DNA testing.
• The rest of the V region between the hypervariable regions are called framework regions.
• The DNA match was based on one of seven small segments taken from the hypervariable regions.
• Humanised antibodies are produced by grafting murine hypervariable regions on amino acid domains into human antibodies.
• Still can't find out what / where a hypervariable region is in that context.
• Hypervariable minisatellites have core units 9 64 bp long and are found mainly at the centromeric regions.
• The residues that form the binding site for a given antigen, are selected among the hypervariable residues.
• The C-terminus of Rab proteins varies in length and sequence and is referred to as hypervariable.
• For example, the QKRAA sequence is an amino acid motif in the third hypervariable region of HLA-DRB1 * 0401.
• Thus, this hypervariable region of VP2 is the obvious target for the molecular techniques applied for IBDV detection and strain variation studies.
• Since most sequence variation associated with immunoglobulins and T cell receptors are found in the CDRs, these regions are sometimes referred to as " hypervariable regions ".
• In his 1998 study, utilising polymorphic loci from seven hypervariable autosomal DNA loci, an autocorrelation analysis produced a clinal pattern closely matching that in Cavalli-Sforza s study.
• The combined sequence of variable light chain ( V L ) and variable heavy chain ( V H ) creates three hypervariable regions ( HV1, HV2, and HV3 ).
• Building on this observation, Jeremy Barr and Rohwer ( Barr et al . 2013; 2015 ) showed that bacteriophage bind to mucus through hypervariable protein domains displayed on the capsid.
• To circumvent this problem, Greg Winter and his colleagues humanised Campath-1, by extracting the hypervariable loops that had specificity for CD52 and grafting them onto a human antibody framework.
• Family Tree DNA's first mtDNA tests were for HVR1 ( hypervariable region 1 ) of the mtDNA . Eventually, they added a Plus test that tested for both HVR1 and HVR2.
• The largest ectodomain of ASCT1 and ASCT2, extracellular loop 2 ( ECL2 ), contains at its C-terminus a 21 residue hypervariable region between human, mouse, and hamster receptors.
• Version 3 of van Oven's Phylotree defines K1a1b1a by the highly polymorphic 114 in the second hypervariable region, 10978 and 12954 in the coding region, and 16234 in the first hypervariable region.
• Version 3 of van Oven's Phylotree defines K1a1b1a by the highly polymorphic 114 in the second hypervariable region, 10978 and 12954 in the coding region, and 16234 in the first hypervariable region.