hypofunction การใช้

• Variations in individual sensitivity to glucocorticoid medications may be due to either GR hypofunction or hyperfunction.
• If elderly patients are treated with eperisone, a reduced dose is recommended, and the patient should be closely monitored for signs of psychological hypofunction during treatment.
• The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA receptors.
• For example, NMDA receptor hypofunction that occurs as the brain ages may be partially responsible for mood, nightmares, catatonia, ataxia, anesthesia, and learning and memory deficits.
• Hypofunction of serotonergic neurones arising from the dorsal raphe nucleus and GABAergic neurones that are widely distributed in the brain may result in a lack of inhibitory effect on the putative GAD pathway.