ibdv การใช้

• Diseases associated with this genus include : IBDV causes severe inflammation of the bursa of fabricius.
• Passive immunity may protect against challenge with homologous IBDV, as does previous infection with homologous avirulent strains.
• At least six antigenic subtypes of IBDV serotype 1 have been identified by " in vitro " cross-neutralization assay.
• Thus, this hypervariable region of VP2 is the obvious target for the molecular techniques applied for IBDV detection and strain variation studies.
• Infectious bursal disease virus ( IBDV ) was first discovered in Gumboro in 1962, and thus has been known as Gumboro disease.
• IBDV genome consists of two segments, A and B, which are enclosed within a nonenveloped kb ) encodes VP1, the putative viral RNA polymerase.
• Concurrent immunosuppressive infections are an emerging concern in the poultry industry whereby early infection with IBDV causes the MD virus to come out of dormancy and contribute to active disease.
• IBDV is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus " Avibirnavirus " of family " Birnaviridae ".
• In recent years, very virulent strains of IBDV ( vvIBDV ), causing severe mortality in chicken, have emerged in Europe, Latin America, South-East Asia, Africa and the Middle East.
• With the advent of highly sensitive molecular techniques, such as reverse transcription polymerase chain reaction ( RT-PCR ) and restriction fragment length polymorphism ( RFLP ), it became possible to detect the vvIBDV, to differentiate IBDV strains, and to use such information in studying the molecular epidemiology of the virus.
• "' Infectious bursal disease "'( also known as IBD, Gumboro Disease, Infectious Bursitis and Infectious Avian Nephrosis ) is a highly contagious disease of young chickens caused by " infectious bursal disease virus " ( IBDV ), characterized by immunosuppression and mortality generally at 3 to 6 weeks of age.