integrins การใช้

• Ligands for integrins include fibronectin, vitronectin, collagen and laminin.
• The V-region contains the binding site for ?4?1 integrins.
• CD47 interacts with several membrane integrins, most commonly integrin avb3.
• Beta-1 integrins interact with many alpha integrin chains.
• Fibronectins bind to ECM macromolecules and facilitate their binding to transmembrane integrins.
• Chondrocyte surface mechano-receptors include CD44, annexin V and integrins.
• A given chain may combine with multiple partners resulting in different integrins.
• He was also the first to determine the crystal structures of integrins.
• The cells comply, adding proteins, called integrins, to their membranes.
• Fibronectin domains of L1 protein are also capable of binding cell surface integrins.
• Connection between focal adhesions and proteins of the extracellular matrix generally involves integrins.
• Integrins are heterodimers which are formed from one beta and one alpha subunit.
• Interactions with CD63 may therefore affect the trafficking and function of ?2 integrins.
• In addition to adhesion, many integrins are known to facilitate signal transduction.
• But so far, researchers have failed to activate mammalian eggs by targeting integrins.
• This ?-I domain is the binding site for ligands of such integrins.
• Cells adhere to a substrate through their integrins.
• Specifically, targeting integrins associated with RTKs is an emerging approach for inhibiting angiogenesis.
• Integrins can assume several different well-defined shapes or " conformational states ".
• Then, viral protein gH / gL interacts with cellular ?v?6 / ?v?8 integrins.