intracoronary การใช้

• Administration of Mydicar occurs via an intracoronary injection of the drug.
• A damper on the immediate use of intracoronary stents was subacute thrombosis.
• One method involves the use of intracoronary radiation at the time of stent insertion.
• Alternative treatments include brachytherapy, or intracoronary radiation.
• Other alternative injection routes have been studied, namely injection via sternotomy, endomyocardial and intracoronary routes.
• Stent technology improved rapidly, and in 1989 the Palmaz-Schatz balloon-expandable intracoronary stent was developed.
• He is recognized for the development of methods for the automatic quantification of stent characteristics on intracoronary optical coherence tomography images.
• Together with Prof . Brett E . Bouma, he is recognized as one of the inventors of Intracoronary optical coherence tomography.
• Subacute thrombosis rates with intracoronary stents proved to be about 3.7 percent, higher than the rates seen after balloon angioplasty.
• The high-resolution of OCT imaging allows to assess with high accuracy vessel lumen area, wall microstructure, intracoronary stent apposition and expansion.
• It was quickly realized that restenosis rates were significantly lower in individuals who received an intracoronary stent when compared to those who underwent just balloon angioplasty.
• The cassette, which is loaded with the interventional devices and connected to the guiding catheters, imposes axial and rotational forces on the intracoronary devices.
• Testing can also take place in the coronary arteries themselves but this is invasive and not normally conducted unless there is a clinical reason for intracoronary catheterisation.
• While the rates of subacute thrombosis and bleeding complications associated with stent placement were high, by 1999 nearly 85 % of all PCI procedures included intracoronary stenting.
• Early clinical studies with protein-based therapeutics largely focused on the intravenous or intracoronary administration of a particular growth factor to stimulate angiogenesis in the affected tissue or organ.
• Current clinical uses of IVUS technology include checking how to treat complex lesions before angioplasty and checking how well an intracoronary stent has been deployed within a coronary artery after angioplasty.
• His current research interests include brachytherapy for restenosis prevention bioabsorbable / biodegradable stents, HDL therapy, intracoronary imaging, valvular heart disease and catheter-based treatment of renal denervation.
• Indeed, the intracoronary route is the most straightforward cell delivery route as associated with intramyocardial cellular retention; rentention rates are however low, i . e . exceed 10 %.
• While the use of intracoronary stents do not improve the short term outcomes in primary PCI, the use of stents is widespread because of the decreased rates of procedures to treat restenosis compared to balloon angioplasty.
• He finished medical school in Amsterdam and subsequently received his PhD degree cum laude in 2001 on intracoronary derived physiological parameters for clinical decision making at the Academic Medical Center ( AMC ) in Amsterdam under supervision of prof.