intraneuronal การใช้

• This activity is actually inhibited by glutamate and other conditions that elevate intraneuronal calcium.
• Treatment was seen to decrease the intraneuronal levels of the more aggressive A?42 molecule when compared to the control mice.
• One of the few known biological changes seen in mTBI is the massive intraneuronal accumulation of a protein called Tau in very specific and recognizable patterns in the human brain.
• Thus the goal of this study is to develop an animal model of r-mTBI model that will allow the tracking of progressive intraneuronal tau alterations that can be correlated with behavioral dysfunction, fluorescent in situ hybridization, and gene expression signatures.
• By binding to peripheral motor neuron terminals, the toxin enters the nerve axons, and is transported across retrograde intraneuronal transport, until it reaches the central nervous system, where it rapidly binds to gangliosides at the presynaptic membrane of inhibitory motor nerve endings.