isoenzyme การใช้

• CAIX is a transmembrane protein and is a tumor-associated carbonic anhydrase isoenzyme.
• It belongs to the creatine kinase isoenzyme family.
• Drugs that interfere with the activity of the CYP3A4 isoenzyme can increase serum dofetilide levels.
• This gene encodes the erythrocyte acylphosphatase isoenzyme.
• LDH isoenzyme expression is tissue-dependent.
• This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin.
• Only Zanamivir shows moderate inhibition activity for hNEU . Isoenzyme selective inhibitors could potentially be very important.
• Furthermore, the isoenzyme determination has been used extensively as an indication for myocardial damage in heart attacks.
• FMO3 is the main flavin-containing monooxygenase isoenzyme that is expressed in the liver of adult humans.
• CYP3A4 isoenzyme is the most predominant isoform involved in metabolism of lovastatin, simvastatin, atorvastatin and cerivastatin.
• It has been proposed that the MGAT4A isoenzyme acts as a toggle for developing of type 2 diabetes.
• However, isoenzyme analysis reveals that it is more closely related to " Rauvolfia tetraphylla L ".
• About 20 percent of dofetilide is metabolized in the liver via the CYP3A4 isoenzyme of the cytochrome P450 enzyme system.
• MCPP is metabolized via the CYP2D6 isoenzyme by hydroxylation to p-hydroxy-mCPP ( OH-mCPP ).
• Hence, this isoenzyme is an important regulator of glycolysis and additional functions in other novel roles that have recently emerged.
• Finally C9-triazole derivatives of DANA containing an alkoxy group with a nanomolar activity against hNEU4 isoenzyme have been reported.
• With a 500-fold selectivity for hNEU4, this is the highest reported selectivity for a hNEU isoenzyme to date.
• An isoenzyme of glycogen phosphorylase exists in the liver sensitive to glucose concentration, as the liver acts as a glucose exporter.
• This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration.
• The majority of flecainide is eliminated by the kidneys, with the remainder metabolized by the cytochrome P450 2D6 isoenzyme in the liver.