lipocortin 1 การใช้

• D ) the N-terminally truncated form of the chemotactic chemokine, CCL23, termed CCL23 splice variant CCL23? ( amino acids 22 137 ) and SHAAGtide, which is a product of CCL23? cleavage by pro-inflammatory proteases ( pro-inflammatory ); e ) two N-acetyl peptides, Ac2 26 and Ac9 25 of Annexin A1 ( ANXA1 or lipocortin 1 ), which at high concentrations fully stimulate neutrophil functions but at lower concentrations leave neutrophils desensitized ( i . e . unresponsive ) to the chemokine IL-8 ( CXCL8 ) ( pro-inflammatory and anti-inflammatory, respectively, highlighting the duality of FPR2 / ALX functions in inflammation );