liposomal การใช้

• Liposomal preparations of amphotericin B are more effective than deoxycholate preparations.
• Liposomal anti-fungals are easier to tolerate, but more expensive.
• Liposomal cisplatin has received orphan drug designation for pancreatic cancer from EMEA.
• Like Doxil, the liposomal encapsulation of the doxorubicin limits the cardiotoxicity.
• He also worked on the therapy of systemic fungal infections by developing liposomal formulations.
• Fungisome is a generic liposomal complex of amphotericin B marketed by Lifecare Innovations of India.
• "' OSI-7904L "'is a novel noncompetitive liposomal thymidylate synthase inhibitor.
• The drug is a liposomal formulation of amphotericin B, which is used to treat severe fungal infections.
• The approval heightens the competition in the market for new versions of amphotericin B known as liposomal formulations.
• AmBisome ( LAMB ) is a liposomal formulation of amphotericin B for unilamellar vesicles that contain amphotericin B.
• For multiple site or CNS aspergillosis a combination therapy of voriconazole and liposomal amphotericin B should be considered.
• Vincristine ( Liposomal ) : P-glycoprotein / ABCB1 Inducers may decrease the serum concentration of vincristine.
• Additionally, liposomal nystatin appears to cause fewer cases of and less severe nephrotoxicity than observed with amphotericin B.
• The treatment of choice for visceral leishmaniasis acquired in India is now Amphotericin B in its various liposomal preparations.
• Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
• Chemical differences may exist; a different liposomal preparations, or biosimilar drugs demonstrating pharmacodynamic or clinical equivalence is more challenging.
• The FDA usually follows advisory committee recommendations, meaning the first liposomal drug could be available by the end of the year.
• And four companies are furiously testing liposomal agents in Americans who have everything from breast and lung cancer to killer fungal diseases.
• LECIVA-S70 : Pure phospholipid fraction of soya lecithin for oral as well as topical liposomal formulations like ketoconazole and flucanazole.
• Surprisingly, liposomal fatty acyl chains are more restricted at 5th and 7th carbon positions as compared at these positions in thylakoid membranes.