lynestrenol การใช้

• The drug is an isomer of lynestrenol with the double bond between C5 and C6.
• It is an isomer of the related 19-nortestosterone derivative progestins lynestrenol and cingestol.
• Lynestrenol and its metabolites are predominantly excreted in the urine, less through feces, active metabolite norethisterone elimination half-life being 16 to 17 hours.
• Other progestogens including medroxyprogesterone acetate, lynestrenol, allylestrenol, dydrogesterone, and normethandrone have also been found to be effective for migraine in a high percentage of women.
• A number of prodrugs of NET, including norethisterone acetate ( NETA ), norethisterone enanthate ( NETE ), etynodiol diacetate, lynestrenol, and quingestanol acetate, have been marketed as well.
• Among the testosterone derivatives, and in no particular order, levonorgestrel, norgestrel, norgestrienone, ethisterone, gestrinone, danazol, normethandrone, and norvinisterone have the greatest androgenic activity, while norethisterone and its prodrugs ( norethisterone acetate, norethisterone enanthate, lynestrenol, etynodiol diacetate, and quingestanol acetate ) have moderate activity.