metrazol การใช้

• Furthermore, since 1935, metrazol, an schizophrenics, with great success.
• These included the convulsive therapies ( cardiazol / metrazol therapy and electroconvulsive therapy ), deep sleep therapy and psychosurgery.
• They only charged patients at half price, and often received payment in the form of gifts . however Metrazol therapy was generally abandoned in 1941.
• Electric shock treatment quickly replaced insulin and Metrazol as the favourite form of shock treatment, and became the most effective method of controlling troublesome asylum inmates.
• In 1939 it was brought to England and replaced cardiazol ( metrazol ) as the preferred method of inducing seizures in convulsion therapy in British mental hospitals.
• Though convulsive treatments for mental illness had been conducted earlier with the use of metrazol, this was the first therapeutic seizure in medical history induced by electric current.
• Early in his work Meduna replaced camphor with pentylenetetrazol ( Metrazol ), an intravenous agent that induced seizures immediately compared with the long delay of 15 to 45 minutes after intramuscular camphor.
• Some psychiatrists regarded seizures as therapeutic and patients were sometimes also given electroconvulsive therapy or cardiazol / metrazol convulsive therapy during the coma, or on the day of the week when they didn t have insulin treatment.
• The first clinical applications were in identifying the sudden bursts of high voltage slow frequencies during seizures, both spontaneous and induced by the chemical pentylenetetrazol ( Metrazol ), by electricity in electroshock, and in the coma induced by insulin.
• Although electroshocked pig brain therapy was used by a few psychiatrists in Italy, France and Brazil it did not become as popular as ECT, which soon replaced metrazol therapy all over the world because it was cheaper, less frightening and more convenient.
• Different kinds of convulsive therapies, or  shock therapies ( insulin shock, metrazol shock, electroshock ), were used for all manner of patients, as these were the only treatments with any consistent efficacy yet discovered ( though they were only truly effective on a small number ).