mitogenic การใช้

• It has been postulated to play a role in mitogenic signaling.
• In many mitogenic and developmental proteins such as LDL-receptor.
• This reduces the sensitivity of stem cells to mitogenic signals by inhibiting cyclin-CDK complexes.
• Moreover, Sap1a-mediated transcription is activated by mitogenic signals but not by cell stress.
• Dual-specificity protein phosphatases ( DSPs ) regulate mitogenic signal transduction and control the cell cycle.
• HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein.
• A variety of mitogenic signals engage the MAPK pathway and promote cell growth and differentiation through a kinase cascade.
• RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.
• The four members of this family are mitogenic factors for cells of N-terminal domain, the CUB domain.
• However, its authors suggest it might be also applied to CD28 triggering by superagonistic antibodies ( mitogenic antibodies ).
• Alexander Gurwitsch, who discovered the existence of biophotons, was awarded the Stalin Prize in 1941 for his mitogenic radiation work.
• Receptors involved in mitogenic pathways that lead to the increased production of cancer cells there have also been targeted by siRNA molecules.
• Increasing cyclin D1 levels during the G1 phase is induced by mitogenic growth factors primarily through Ras mediated pathways, and hormones.
• The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines.
• The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.
• A mitogenic effect of this protein on experimental breast cells lines MCF10A, MCF7, BT474, MDA-MB231 and T47D was detected.
• Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation.
• The mitogenic role of MDM2 is also needed for wound healing upon tissue injury, while MDM2 inhibition impairs re-epithelialization upon epithelial damage.
• Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
• Cell proliferation in the developing CNS reflects the action of positive ( mitogenic growth factors ) and negative ( anti-proliferative factors ) regulators.