multivesicular การใช้

• The process of microautophagic vesicle formation is similar to multivesicular bodies formation process
• Multivesicular bodies are endosomal compartments that sort ubiquitinated membrane proteins by incorporating them into vesicles.
• There is also growing evidence of a large number of multivesicular bodies and other endocytic activity.
• A less desirable form are multivesicular liposomes in which one vesicle contains one or more smaller vesicles.
• CHMP5 belongs to the chromatin-modifying protein / charged multivesicular body protein ( CHMP ) family.
• Once formed, the endosome combines with a structure known as a multivesicular body ( MVB ).
• Recently his laboratory has discovered a close relationship between the canonical Wnt pathway, multivesicular endosomes and protein degradation.
• It is because of these vesicles that the endosome is sometimes known as a " multivesicular body ".
• This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body / late endosome pathway.
• This gene encodes a protein that acts in the sorting of transmembrane proteins into lysosomes / vacuoles via the multivesicular body ( MVB ) pathway.
• This work yielded the first description of crinophagy, the process by which secretory granules are taken up and disposed of in multivesicular bodies and lysosomes.
• This gene encodes a member of the CHMP / Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes.
• The nucleic acid material becomes reorganized and the distinction between multivesicular bodies all appear to swell, though this can be best seen in the mitochondria which appear to swell first.
• Multivesicular release ( MVR ) occurs at Schaffer collateral-CA1 synapses when P is elevated by facilitation and that MVR may be a phenomenon common to many synapses throughout the central nervous system.
• They include 1 ) direct translocation of proteins across the plasma membrane likely through membrane transporters, 2 ) blebbing, 3 ) lysosomal secretion, and 4 ) release via exosomes derived from multivesicular bodies.
• These proteins are components of ESCRT-III ( endosomal sorting complex required for transport III ), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies ( MVBs ).
• Within the perikarya of pars compacta neurons, DAT was localized primarily to rough and smooth endoplasmic reticulum, Golgi complex, and multivesicular bodies, identifying probable sites of synthesis, modification, transport, and degradation.
• The Emr lab recently identified the ESCRT complexes, which are the first components of a molecular machine required for receptor down-regulation at the endosome ( multivesicular body ), a late step in cytokinesis, and for the budding and release of HIV.
• TSG101 seems to play an important role in the pathogenesis of HIV . In uninfected cells, TSG101 functions in the biogenesis of the multivesicular body ( MVB ), which suggests that HIV may bind TSG101 in order to gain access to the downstream machinery that catalyzes MVB vesicle budding.