neopterin การใช้

• Neopterin serves as a marker of cellular immune system activation.
• Neopterin belongs to the chemical group known as pteridines.
• Neopterin concentrations usually correlate with the extent and activity of the disease, and are also useful to monitor during therapy in these patients.
• Elevated neopterin concentrations are among the best predictors of adverse outcome in patients with HIV infection, in cardiovascular disease and in various types of cancer.
• High neopterin production is associated with increased production of reactive oxygen species, neopterin concentrations also allow to estimate the extent of oxidative stress elicited by the immune system.
• High neopterin production is associated with increased production of reactive oxygen species, neopterin concentrations also allow to estimate the extent of oxidative stress elicited by the immune system.
• Increased numbers of T-Cells presenting activation markers, levels of neopterin, IFN gamma, sTNFR, and IL-2 receptors have been observed in depression.
• Measurement of neopterin concentrations in body fluids like blood serum, cerebrospinal fluid or urine provides information about activation of cellular immune activation in humans under the control of T helper cells type 1.
• Sometimes a lumbar puncture is performed to measure concentrations of biopterin and neopterin, which can help determine the exact form of dopamine-responsive movement disorder : early onset parkinsonism ( reduced biopterin and normal neopterin ), GTP cyclohydrolase I deficiency ( both decreased ) and tyrosine hydroxylase deficiency ( both normal ).
• Sometimes a lumbar puncture is performed to measure concentrations of biopterin and neopterin, which can help determine the exact form of dopamine-responsive movement disorder : early onset parkinsonism ( reduced biopterin and normal neopterin ), GTP cyclohydrolase I deficiency ( both decreased ) and tyrosine hydroxylase deficiency ( both normal ).