nondividing การใช้

• Neurons typically remain in G0, a nondividing, nonreplicating phase of the cell cycle.
• This study showed that the AAV vector was successful at efficiently transferring DNA into nondividing cells.
• If a lentivirus is needed because of its ability to infect nondividing cells, then animal viruses could be used instead of HIV.
• Most important, it is one of a small class of viruses, known as lentiviruses, that can incorporate genes into the chromosomes even of nondividing cells.
• Normal cells are maintained in a nondividing state by antigrowth signals, which cancer cells learn to evade through genetic changes producing " insensitivity to antigrowth signals ".
• Using the new viral carrier, Verma and his team showed that genes could be inserted into nondividing blood cells and also into rat brain cells, which are not dividing.
• Centrocyte can also refer to a cell with a protoplasm that contains single and double granules of varying size stainable with hematoxylin, as seen in lesions of lichen planus, or a nondividing, activated B cell that expresses membrane immunoglobulin.
• If the new carrier works as well as it has in the experiments, " we would have a shot " at putting genes into nondividing cells, commented Dr . John Belmont of the Baylor University Center for Gene Therapy.
• Because vectors currently available can't insert their cargo into the chromosomes of a nondividing cell, gene therapy researchers have had to go through a detailed process : remove cells of organs they are trying to repair, grow them in the lab and prod them into division, insert the desired genes and then return the cells to the patient.