nuclein การใช้

• Kossel showed that the substance, called " nuclein ", consisted of a protein component and a non-protein component.
• Originally discovered in 1900 by Alberto Ascoli, it was isolated by hydrolysis of yeast nuclein; it was also found in bovine thymus and spleen, herring sperm, and wheat germ.
• As a result of his work on the action of phlorhizin, a glucoside provoking glycosuria, and another one on nuclein metabolism in man, he was appointed 玃rivatdozent?( Lecturer ) in 1900.
• The importance of Miescher's discovery was not apparent until Albrecht Kossel ( a German physiologist specializing in the physiological chemistry of the cell and its nucleus and of proteins ) carried out research on the chemical structure of nuclein.
• Miescher isolated various phosphate-rich chemicals, which he called " nuclein " ( now nucleic acids ), from the nuclei of white blood cells in 1869 in Felix Hoppe-Seyler's laboratory at the University of T黚ingen, Germany,
• Friedrich Miescher ( 1844 1895 ) discovered a substance he called " nuclein " in 1869 . Somewhat later, he isolated a pure sample of the material now known as DNA from the sperm of salmon, and in 1889 his pupil, Richard Altmann, named it " nucleic acid ".