omphalitis การใช้

• Omphalitis can quickly progress to sepsis and presents a potentially life-threatening infection.
• In fact, even in cases of omphalitis without evidence of more serious infection such as necrotizing fasciitis, mortality is high ( in the 10 % range ).
• Like many bacterial infections, omphalitis is more common in those patients who have a weakened or deficient immune system or who are hospitalized and subject to invasive procedures.
• Infections such as omphalitis, pneumonia, gingivitis, and peritonitis are common and often life-threatening due to the infant's inability to properly destroy the invading pathogens.
• In resource-limited settings, gentian violet is used to manage burn wounds, inflammation of the umbilical cord stump ( omphalitis ) in the neonatal period, oral candidiasis in HIV-infected patients and mouth ulcers in children with measles.
• These infections include cellulitis of the site of fetal monitoring ( caused by " Bacterodes " spp . ), bacteremia, aspiration pneumonia ( caused by " Bacterodes " spp . ), conjunctivitis ( caused by clostridia, ) omphalitis ( caused by mixed flora ), and infant botulism.
• Clinically, neonates with omphalitis present within the first two weeks of life with signs and symptoms of a skin infection ( cellulitis ) around the umbilical stump ( redness, warmth, swelling, pain ), pus from the umbilical stump, fever, fast heart rate ( tachycardia ), low blood pressure ( hypotension ), somnolence, poor feeding, and yellow skin ( jaundice ).