oncogenicity การใช้

• Indirect viral oncogenicity involves chronic nonspecific inflammation occurring over decades of infection, as is the case for HCV-induced liver cancer.
• Some antigenic variation can occur within subgroups, and all strains are oncogenic, but oncogenicity and the ability to replicate varies between subgroups.
• The Bcr-Abl oncoprotein oligomerisation domain found at the N-terminus of BCR is essential for the oncogenicity of the BCR-ABL fusion protein.
• Since that discovery, multiple studies have demonstrated an incidence of approximately 1 % in lung cancers, demonstrated oncogenicity, and showed that inhibition of tumor cells bearing " ROS1 " gene fusions by crizotinib or other " ROS1 " tyrosine kinase inhibitors was effective in vitro.