piebaldism การใช้

• Piebaldism is found in nearly every species of mammal.
• Piebaldism is completely unrelated to acquired or infectious conditions such as vitiligo or poliosis.
• Conditions associated with abnormalities in the migration of melanoblasts are known collectively as piebaldism.
• Piebaldism and amelanism are distinct conditions.
• Children with piebaldism, for instance, are born with a white forelock and colorless patches on their forehead and trunk.
• "' Piebaldism "'is a rare Native Americans of the Mandan tribe who were affected by piebaldism.
• "' Piebaldism "'is a rare Native Americans of the Mandan tribe who were affected by piebaldism.
• Piebaldism differs from albinism in that the affected cells maintain the ability to produce pigment but have that specific function turned off.
• Historically, persons with extensive piebaldism have experienced abuse of the sort still suffered in the present by albinos, especially in Africa.
• Piebaldism is a kind of neurocristopathy, involving defects of various neural crest cell lineages that include melanocytes, but also involving many other tissues derived from the neural crest.
• Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
• "Pie " is a word for multi-colored and " bald " is related to a root word for " skin . " Although piebaldism may visually appear to be partial albinism, it is a fundamentally different condition.
• Human piebaldism has been observed to be associated with a very wide range and varying degrees of endocrine disorders, and is occasionally found together with heterochromia of the irises, congenital deafness, or incomplete gastrointestinal tract development, possibly all with the common cause of premature cutting off of human fetal growth hormone during gestation.
• Accepted examples are piebaldism, Waardenburg syndrome, Hirschsprung disease, Ondine's curse ( congenital central hypoventilation syndrome ), pheochromocytoma, paraganglioma, Merkel cell carcinoma, multiple endocrine neoplasia, neurofibromatosis type I, CHARGE syndrome, familial dysautonomia, DiGeorge syndrome, Axenfeld-Rieger syndrome, Goldenhar syndrome ( a . k . a . hemifacial microsomia ), craniofrontonasal syndrome, congenital melanocytic nevus, melanoma, and certain congenital heart defects of the outflow tract, in particular.