poliovirus การใช้

• Poliovirus is composed of an RNA genome and a protein capsid.
• The first IRES to be discovered was found in poliovirus RNA.
• Paralytic poliomyelitis occurs in less than 1 % of poliovirus infections.
• Wild poliovirus is present in Afghanistan, though in limited areas.
• Poliovirus infects host cells through inhibition of transcription machinery and function.
• Its best known subtype is poliovirus, the cause of poliomyelitis.
• The oral Sabin polio vaccine was a weakened form of the poliovirus.
• The molecular mechanisms by which poliovirus causes paralytic disease are poorly understood.
• Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper.
• Drake demonstrated that poliovirus is able to undergo multiplicity reactivation.
• Infections by poliovirus most often cause the mildest of symptoms.
• The country has not yet interrupted transmission of wild poliovirus.
• An international collaboration to create a synthetic vaccine for poliovirus is announced.
• Type P2 wild poliovirus eradicated from India and the World.
• Therefore, receptor expression does not explain why poliovirus preferentially infects certain tissues.
• Mice were engineered to express a human receptor to poliovirus ( hPVR ).
• In the intestines, Sabin had discovered, the poliovirus multiplied and attacked.
• There are three serotypes of poliovirus, PV1, PV2, and PV3.
• A concern is the presence of circulating vaccine-derived polioviruses ( cVDPV ).
• Poliovirus is a positive-stranded RNA virus.