polycistronic การใช้

• After introducing 9-base pair polycistronic stretch of sequence.
• The operon is said to be polycistronic, whereas ordinary genes are said to be monocistronic.
• Bacterial operons are polycistronic transcripts that are able to produce multiple proteins from one mRNA transcript.
• It has been shown that RyhB has a role in targeting the polycistronic transcript iscRSUA for differential degradation.
• When "'transcription "'takes place on the heavy strand a polycistronic transcript is created.
• In general, expression of prokaryotic operons leads to the generation of polycistronic mRNAs, while eukaryotic operons lead to monocistronic mRNAs.
• However, the definition of an operon does not require the mRNA to be polycistronic, though in practice, it usually is.
• They have been found in several species to be responsible for separating polycistronic transcripts into single gene mRNAs, and in others to splice onto monocistronic transcripts.
• The Cp promoter promotes the transcription of all the EBNA genes from a polycistronic mRNA . The Q promoter ( Qp ) promotes the transcription of EBNA1.
• An operon contains one or more structural genes which are generally transcribed into one polycistronic mRNA ( a single mRNA molecule that codes for more than one protein ).
• The 517 polycistronic operons are listed in a 2009 study describing the global changes in transcription that occur in " L . monocytogenes " under different conditions.
• Later research showed that MazG is transcribed in the same polycistronic mRNA as MazE and MazF, and that MazG bound the MazF toxin to further inhibit its activity.
• The "'IscR stability element "'is a conserved secondary structure found in the intergenic regions of iscRSUA polycistronic mRNA . This secondary structure prevents the degradation of the iscR mRNA.
• "' SL2 RNA "'is a non-coding RNA involved in polycistronic transcription units and the presence of SL2 on an mRNA is an indication the gene is in an operon.
• Note that the base word " cistron " is no longer used in genetics, and has been replaced by intron and exon in eukaryotic mRNA . However, the mRNA found in bacteria is mainly polycistronic.
• Each ES is a polycistronic unit, containing a number of Expression Site-Associated Genes ( ESAGs ) all expressed along with the active VSG . While multiple ES exist, only a single one is ever active at one time.
• In this phase, same L protein acts as a replicase and ignore the gene junctions to generate a polycistronic anti-genomic analogue that acts as a template for further rounds of replication to generate many more copies of the genome RNA . This progeny genome RNA upon packaging by viral proteins bud out as mature virus particles.
• For example, in " Leishmania ", protein-coding genes are understood to be organized as large polycistronic units in a head-to-head or tail-to-tail manner; RNA polymerase II transcribes long polycistronic messages in the absence of defined RNA pol II promoters, and " Leishmania " has unique features with respect to the regulation of gene expression in response to changes in the environment.
• For example, in " Leishmania ", protein-coding genes are understood to be organized as large polycistronic units in a head-to-head or tail-to-tail manner; RNA polymerase II transcribes long polycistronic messages in the absence of defined RNA pol II promoters, and " Leishmania " has unique features with respect to the regulation of gene expression in response to changes in the environment.