postmeiotic การใช้
- In Drosophila, Fzo is found in postmeiotic spermatids and the dysfunction of this protein results in male sterility.
- The postmeiotic phase of mouse spermatogenesis is very sensitive to environmental genotoxic agents, because as male germ cells form mature spermatozoa they progressively lose the ability to repair DNA damage.
- The postmeiotic phase of mouse spermatogenesis is very sensitive to environmental genotoxic agents, because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage.
- It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes M transition in fruitfly but in mice the primary defect is postmeiotic at round spermatid stage.
- The isozymes have 87-88 % identical amino acid sequence identity and though they are structurally and functionally similar, they have different localizations : PGK2, encoded by an autosomal gene, is unique to meiotic and postmeiotic spermatogenic cells, while PGK1, encoded on the X-chromosome, is ubiquitously expressed in all cells.