postrema การใช้

• These project to the area postrema and nucleus tractus solitarii in the brain.
• The area postrema and nucleus tractus solitarii signal to the subfornical organ and to the lateral parabrachial nucleus.
• PDE4 mRNAs are transcribed more in the area postrema and the CTZ than anywhere else in the brainstem.
• There are also studies still currently underway to determine the effect of ablation of the area postrema on hypertension and cardiovascular function.
• However, it is known that the area postrema is the locus, or site, of the chemoreceptor trigger zone for vomiting.
• For example, studies in rats and rabbits indicate that angiotensin II-dependent hypertension is abolished by lesioning of the area postrema.
• This suggests that the neurons that express H-channels in the CTZ and area postrema are involved in nausea and the emetic response.
• Other studies have shown that lesions to the area postrema and the parabrachial nucleus of the pons but not the nucleus of the solitary tract
• By the way the " vomiting centre " is the area postrema . talk ) 22 : 40, 27 May 2016 ( UTC)
• {{ quote | text = " Nec tibi cura canum fuerit postrema; sed una Veloces Spartae catulos, acremque Molossum, Pasce sero pingui :"
• These actions, which are mostly carried out via a glucose-sensitive part of the brain stem, the area postrema, may be over-ridden during hypoglycemia.
• The mechanism for this physiological reaction is still not fully understood, but the area postrema's ability to regulate cardiovascular function presents a very interesting direction for neuroendocrinology.
• The area postrema also has integrative capacities that enable it to send major and minor efferents to sections of the brain involved in the autonomic control of cardiovascular and respiratory activities.
• The clinical development of PDE4 inhibitors has been hampered by their potent emetic effects, which appear to be related to their inhibition of PDE4D which is expressed in the area postrema.
• On section it is seen that the funiculus separans is formed by a strip of thickened ependyma, and the area postrema by loose, highly vascular, neuroglial tissue containing nerve cells of moderate size.
• The lower end of the vagal trigone is crossed by a narrow translucent ridge, the funiculus separans, and between this funiculus and the clava, is a small tongue-shaped area, the area postrema.
• However, given that NK1Rs are unprotected by a blood brain barrier in the area postrema just adjacent to neuronal structures in the medulla, and the activity of sendide ( the peptide based NK1RA ) against cisplatin-induced emesis in the ferret.
• Epinephrine is produced in small groups of neurons in the human brain which express PNMT; these neurons project from a nucleus that is adjacent ( ventrolateral ) to the area postrema and from a nucleus in the dorsal region of the solitary tract.
• It has been found that ZD7288, which is a H-channel inhibitor, inhibited the acquisition of conditioned taste aversion ( CTA ) in rats and reduced apomorphine-induced c-Fos expression in the area postrema where the CTZ is located.
• Experiments with conventional tracers and immunofluorescence staining have demonstrated peripheral viscerosensory input from the vagus nerve, input from nearby neurons in the NTS and area postrema, and descending input from the medial central nucleus of the amygdala ( CeA ) and paraventricular hypothalamic nucleus ( PVN ).