prodine การใช้

• Unlike its derivative prodine, it was not reported to exhibit optical isomerism.
• There are two isomers of the trans form of prodine, alphaprodine and betaprodine.
• Prodine has similar effects to other opioids, and produces analgesia, sedation and euphoria.
• "' Allylprodine "'is an opioid analgesic that is an analog of prodine.
• "' Prosidol "'is an opioid analgesic that is an analogue of prodine.
• Unlike pethidine, prodine does not produce toxic metabolites and is therefore more suitable for high-dose therapy.
• "' Prodilidine "'is an opioid analgesic which is a ring-contracted analogue of prodine.
• Unlike the pethidine & prodine classes of opioid, the N-allyl homologue of ketobemidone shows antagonist properties as do derivatives substituted on the piperidine ring.
• As with prodine, there are two isomers of meprodine, alpha-meprodine and beta-meprodine, with the alpha isomer having been more widely used.
• It is closely related to the drug prodine, the only difference being that meprodine has an ethyl group rather than a methyl at the 3-position of the piperidine ring.