proerythroblasts การใช้

• The erythroid component consists predominantly or exclusively of proerythroblasts and early basophilic erythroblasts.
• Proerythroblasts arise from the CFU-e ( colony-forming unit cell surface molecule )-positive.
• Precursors of red cells, the proerythroblasts and basophilic erythroblasts also express erythropoietin receptor and are therefore affected by it.
• Proerythroblasts formed in the densely populated colonies of oncogene HSC cultures are strikingly different from those formed in the control colonies.
• However, KLF2 and EKLF have been found to interact in embryonic erythropoiesis . ?-globin and ?-globin in embryonic proerythroblasts.
• It arises from CFU-GEMM ( via BFU-E, which stands for " erythroid burst-forming units " ) and gives rise to proerythroblasts.
• CFU-GEMM gives rise to CFU-GM ( leading to monoblasts and myeloblasts ), CFU-Meg ( leading to megakaryoblasts ), and CFU-E ( leading to proerythroblasts ).
• In this form of AML, levels of erythroblasts can reach up to 94.8 % of all nucleated cells in the bone marrow, and the immature forms of the erythroblasts, the proerythroblasts and basophilic erythroblasts, are more commonly found.