propylhexedrine การใช้
- When amphetamine became a controlled substance, it was replaced by propylhexedrine.
- Levopropylhexedrine is the " S "-enantiomer of propylhexedrine.
- Propylhexedrine is somewhat less potent than structurally similar amphetamines.
- Propylhexedrine is a structural analog of methamphetamine.
- Propylhexedrine was also manufactured by Smith, Kline and French and was marketed under the name Benzedrex.
- The only difference is that propylhexedrine has a saturated cyclohexane ring where methamphetamine has a benzene ring.
- Propylhexedrine is structurally similar to phenylethylamines, with the only structural difference being the substitution of an alicyclic cycloalkylamine.
- Propylhexedrine is most commonly found in Schedule II status ( highest abuse potential, yet with accepted medicinal uses ).
- There is one case of death where a combination of propylhexedrine, acetaminophen, morphine, promethazine, and kratom was detected.
- Propylhexedrine ( Hexahydromethamphetamine, Obesin ) is a stimulant medication, sold over-the-counter in the United States as the cold medication Benzedrex.
- However the study indicates that kratom toxicity was not included as one of the causes of death and that propylhexedrine was the principal cause of death.
- It is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and it has a similar mechanism of action.
- The difference between them is that whereas methamphetamine is an aromatic molecule containing a phenyl group, cyclopentamine and propylhexedrine are entirely aliphatic and contain no delocalized electrons at all.
- Examples of NDRAs include phenethylamine, tyramine, amphetamine, methamphetamine, lisdexamfetamine, cathinone, methcathinone, propylhexedrine, phenmetrazine, pemoline, 4-methylaminorex, and benzylpiperazine.
- Additionally, drugs such as stimulants and sympathomimetics should not be taken along with propylhexedrine, as this can lead to potentially dangerous spikes in blood pressure and irregular heart rhythms.
- In terms of the acyclic part of the molecule, both cyclopentamine and propylhexedrine are the same as methamphetamine, all three molecules containing the 2-methylaminopropyl side-chain.
- Propylhexedrine is not an amphetamine, though it is structurally similar; it is instead a cycloalkylamine, and thus has stimulant effects that are less potent than similarly structured amphetamines, such as methamphetamine.
- The abuse potential of propylhexedrine is fairly limited, due its limited routes of administration : in the United States, Benzedrex is only available as an inhalant, mixed with lavender oil and menthol.
- Propylhexedrine has also seen use in Europe as an appetite suppressant under the trade name Obesin and in the anticonvulsant preparation barbexaclone its " S "-isomer ( levopropylhexedrine or L-propylhexedrine ) is bonded with phenobarbital for the purpose of offsetting the barbiturate-induced sedation.
- Propylhexedrine has also seen use in Europe as an appetite suppressant under the trade name Obesin and in the anticonvulsant preparation barbexaclone its " S "-isomer ( levopropylhexedrine or L-propylhexedrine ) is bonded with phenobarbital for the purpose of offsetting the barbiturate-induced sedation.
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