psoralens การใช้

• Toxins which are associated with PCD include the psoralens.
• Like other psoralens it causes photosensitization of the skin.
• Psoralens are found naturally in citrus fruit, so they are generally considered safe.
• The authors identify psoralens as " the primary candidate causing the hepatotoxic reaction ".
• An additional use for optimized psoralens is for the inactivation of pathogens in blood products.
• High levels of psoralens in celery have caused skin rashes among farm workers harvesting the crop.
• Psoralens are in fact used therapeutically for the treatment of psoriasis, eczema, and vitiligo.
• Psoralens are also used in photopheresis, where they are mixed with the extracted leukocytes before UV radiation is applied.
• _An entree of prime rib of beef with parsley sauce ( heterocyclic amines and psoralens, both carcinogens and mutagens ).
• But it will still have : ethyl alcohol, benzo ( a ) pyrene, ethyl carbamate, furan derivatives, furfural, hydrazines, psoralens, quercetin glycosides and safrole.
• A class of prescription medications known as " psoralens, " used to treat some skin diseases like vitiligio and psoriasis, can also interact with St . John's wort.
• For example, a new insect-resistant variety of celery was found to contain 6, 200 parts per billion of carcinogenic chemicals called psoralens, whereas normal celery had only 800 parts per billion of these chemicals.
• The photochemically reactive sites in psoralens are located at each of the carbon-carbon double bonds in the furan ring ( the five-member ring ) and the pyrone ring ( the six-member ring ).
• He was particularly noted for the total synthesis of heterocyclic drugs and natural products, including porphyrins, camptothecin, saxitoxin, psoralens, antibiotics, antitumor compounds, and opium alkaloids such as morphine, codeine, and hydromorphone.
• The specific causes appear to be chemicals in the juice called furanocoumarins or psoralens that function like " little suicide bombers, " attaching to the enzyme and damaging it so badly that the entire complex disappears from the cell.
• Narrowband ultraviolet B ( NBUVB ) phototherapy lacks the side-effects caused by psoralens and is as effective as PUVA . As with PUVA, treatment is carried out twice weekly in a clinic or every day at home, and there is no need to use psoralen.
• _A fresh relish tray of carrots ( caffeic acid, a carcinogen ), cherry tomatoes ( benzaldehyde, hydrogen peroxide, quercetin glycosides, all carcinogens and the latter two also mutagens ) and celery ( caffeic acid and psoralens, another carcinogen, and furan derivatives, a mutagen ).