reptilase การใช้

• Reptilase, an enzyme found in the venom of Bothrops snakes, has activity similar to thrombin.
• Reptilase also differs from thrombin by releasing fibrinopeptide A, but not fibrinopeptide B, in its cleavage of fibrinogen.
• In blood samples containing heparin, a substance derived from snake venom called batroxobin ( formerly reptilase ) is used instead of thrombin.
• Unlike thrombin, reptilase is resistant to inhibition by antithrombin III . Thus, the reptilase time is not prolonged in blood samples containing heparin, hirudin, or direct thrombin inhibitors, whereas the thrombin time will be prolonged in these samples.
• Unlike thrombin, reptilase is resistant to inhibition by antithrombin III . Thus, the reptilase time is not prolonged in blood samples containing heparin, hirudin, or direct thrombin inhibitors, whereas the thrombin time will be prolonged in these samples.
• "' Batroxobin "', also known as reptilase, is a snake venom produced by " Bothrops atrox " and " Bothrops moojeni ", venomous species of pit viper found east of the Andes in South America.