robertsonian การใช้

• Robertsonian translocations have been seen involving all combinations of acrocentric chromosomes.
• About one in a thousand newborns have a Robertsonian translocation.
• Robertsonian translocations involving chromosome 14 also carry a slight risk of uniparental disomy 14 due to trisomy rescue.
• A balanced translocation or Robertsonian translocation in one of the partners leads to unviable fetuses that are miscarried.
• Males carrying Robertsonian translocations in their chromosomes have significantly higher degree of sperm cell apoptosis and lower concentration.
• The karyotype is separated from that of " A . lutescens " by three Robertsonian translocations.
• Rarely, the same translocation may be present homozygously if heterozygous parents with the same Robertsonian translocation have children.
• A Robertsonian translocation in balanced form results in no excess or deficit of genetic material and causes no health difficulties.
• The reduction in chromosome number is due to centric fusion ( Robertsonian translocation ) of two telocentrics into a single metacentric.
• The other common mechanisms that can give rise to Down syndrome include : a Robertsonian translocation, isochromosome, or ring chromosome.
• A Robertsonian translocation results when the long arms of two acrocentric chromosomes fuse at the centromere and the two short arms are lost.
• The resulting dicentric chromosomes are highly unstable, giving rise to chromosomal translocations, deletions and amplications, such as the Robertsonian translocation.
• Patau syndrome can also occur when part of chromosome 13 becomes attached to another chromosome ( translocated ) before or at conception in a Robertsonian translocation.
• Most people with Robertsonian translocations have only 45 chromosomes in each of their cells, yet all essential genetic material is present, and they appear normal.
• Genetic analysis has confirmed unique sequences of mtDNA, classifying the Japanese raccoon dog as a distinct isolation species, based on evidence of eight Robertsonian translocations.
• The study confirmed the presence of the chromosome translocation known as Robertsonian translocation ( 1; 29 ), a widespread evolutionary marker common to all known tragelaphid species.
• In an acrocentric chromosome the p arm contains genetic material including repeated sequences such as nucleolar organizing regions, and can be translocated without significant harm, as in a balanced Robertsonian translocation.
• In unbalanced forms, Robertsonian translocations cause chromosomal deletions or addition and result in syndromes of multiple malformations, including trisomy 13 ( Patau syndrome ) and trisomy 21 ( Down syndrome ).
• Common Robertsonian translocations are confined to the acrocentric chromosomes 13, 14, 15, 21 and 22, because the short arms of these chromosomes encode for rRNA which is present in multiple copies.
• Przewalski's horse has some biological differences from the domestic horse; unlike domesticated horses and the tarpan, which both have 64 chromosomes, Przewalski's horse has 66 chromosomes due to a Robertsonian translocation.