salvarsan การใช้

• He now had salvarsan for treating syphilitic ulcers and framboesia.
• The drug was given the commercial name Salvarsan.
• It was called Salvarsan 606 because it was the 606th drug that Ehrlich tried.
• Manufactured by Hoechst AG, Salvarsan became the most widely prescribed drug in the world.
• The first effective treatment for syphilis was Salvarsan, developed in 1910 by Paul Ehrlich.
• Salvarsan required improvement as to side effects and solubility and was replaced in 1911 with Neosalvarsan.
• Both salvarsan and neosalvarsan were developed in the laboratory of Paul Ehrlich in Frankfurt, Germany.
• This substance, first called " 606 ", is now known as Arsphenamine or Salvarsan.
• The first effective treatment for a sexually transmitted disease was salvarsan, a treatment for syphilis.
• Salvarsan proved to be amazingly effective, particularly when compared with the conventional therapy of mercury salts.
• Before sulfa came into use there was Arsphenamine } Salvarsan, used starting around 1910 to treat syphilis.
• Both salvarsan and neosalvarsan are prodrugs  that is, they are metabolised into the active drug in the body.
• Ehrlich's discovery of Salvarsan in 1909 for the treatment of syphilis is termed as the first magic bullet.
• In that year it was closed after it was discovered that the disease could be cured within days by applying Salvarsan.
• Salvarsan was the first organic antisyphilitic, and a great improvement over the inorganic hygroscopic powder that was highly unstable in air.
• It became available in 1912 and superseded the more toxic and less water-soluble salvarsan as an effective treatment for syphilis.
• An additional problem was that both Salvarsan and Neosalvarsan had to be stored in sealed vials under a nitrogen atmosphere to prevent oxidation.
• So did the spectroscope, the discovery of radio waves and " the magic bullet, " salvarsan, to treat syphilis.
• There he studied the structure and properties of the popular foreign drug Salvarsan and developed the method of manufacturing a domestic analogue called Arsol.
• His laboratory discovered arsphenamine ( Salvarsan ), the first effective medicinal treatment for syphilis, thereby initiating and also naming the concept of chemotherapy.