spherocytosis การใช้

• The primary defect in hereditary spherocytosis is a deficiency of membrane surface area.
• Measuring iron stores is therefore considered part of the diagnostic approach to hereditary spherocytosis.
• Spherocytosis most often refers to hereditary spherocytosis.
• Spherocytosis most often refers to hereditary spherocytosis.
• OF include hereditary spherocytosis and hypernatremia, while some linked to " decreased"
• In hereditary spherocytosis, red blood cells fail to pass through and get phagocytosed, causing extravascular hemolysis.
• Mutations of spectrin and protein 4.1 are associated with elliptocytosis or spherocytosis and anemia of varying severity.
• Spherocytosis patients who are heterozygous for a hemochromatosis gene may suffer from iron overload despite the hemochromatosis genes being recessive.
• These include regenerative anaemia, spherocytosis, icteric plasma, leukopenia due to neutropenia, thrombocytopenia, eosinopenia and bilirubinuria.
• Castle and his team later characterized the red blood cell defects that are responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis.
• Anemia of chronic disease, hereditary spherocytosis, hereditary hemoglobinopathies ( including some cases of thalassemia minor ) may all present with a normal RDW.
• Risk factors for pigment stones include hemolytic anemias ( such as from sickle-cell disease and hereditary spherocytosis ), cirrhosis, and biliary tract infections.
• In disorders of erythrocyte shape and / or flexibility, such as hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causing extravascular hemolysis.
• Disorders of the proteins in these membranes are associated with many disorders, such as hereditary spherocytosis, hereditary elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria.
• They are most commonly found in immunologically-mediated hemolytic anemias and in hereditary spherocytosis, but the former would have a positive direct Coombs test and the latter would not.
• More importantly erythroid AE1 mutations cause 15 25 % of cases of Hereditary spherocytosis ( a disorder associated with progressive red cell membrane loss ), and also cause the hereditary conditions of Hereditary stomatocytosis and Southeast Asian Ovalocytosis
• Sickle cell anemia is the most common blood disorder that children can inherit from their parents, but hemophilia, von Willebrand's disease and hereditary spherocytosis ( HS ) are all " in the genes ."
• On 15 March 2010, Gerhard Ehninger, head of the German Society for Hematology and Oncology, said that an evaluation of the case points to a light form of a blood anemia called spherocytosis  apparently inherited from her father.
• :* Hereditary spherocytosis syndromes are a group of inherited disorders characterized by defects in the red blood cell's cell membrane, causing the cells to be small, sphere-shaped, and fragile instead of donut-shaped and flexible.
• Hereditary spherocytosis is caused by a variety of molecular defects in the genes that code for the red blood cell proteins spectrin ( beta ), ankyrin, band 3 protein, protein 4.2, and other red blood cell membrane proteins: