spirolactone การใช้

• Spironolactone and eplerenone are steroidal MR antagonists of the spirolactone group.
• "' SC-8109 "'is a steroidal antimineralocorticoid of the spirolactone group that was never marketed.
• Oxprenoate potassium ( RU-28318 ) is not a spirolactone by definition but is a closely related antimineralocorticoid that was never marketed.
• Another example is spironolactone, a potassium-sparing diuretic of the steroidal spirolactone group, which decreases blood pressure by releasing fluid from the body while retaining potassium.
• "' Prorenone "'( developmental code name "'SC-23133 "') is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone that was never marketed.
• "' Drospirenone "'( USAN ), also known as "'1, 2-dihydrospirorenone "', is a steroidal progestin of the spirolactone group used in birth control pills and postmenopausal hormone replacement therapy pills.
• "' Spirolactones "', also known as "'steroid-17?-spirolactones "', "'17?-spirolactosteroids "', or simply "'17?-spirolactones "', are a group of steroids which are both spiro compounds and lactones and which feature these two structural properties combined in the form of a spirolactone antagonists of the mineralocorticoid receptor ( which is activated predominantly by the mineralocorticoid steroid hormone aldosterone ), and have been employed clinically as potassium-sparing diuretics.