sulfinyl การใช้

• Sulfinyl chlorides undergo Friedel Crafts reactions with arenes giving sulfoxides.
• A trifluoroperacetic acid oxidation then provides a general approach to formation of sulfinyl chlorides from sulfenyl chlorides:
• For example, sulfinate esters made from sulfinyl chlorides and menthol can be used to make Grignard reagents.
• The most widely used method for the asymmetric synthesis of " N "-sulfinyl imines is the condensation of enantiopure primary sulfinamides with aldehyde or ketones.
• Condensation of " tert "-butanesulfinamide with an aldehyde or ketone proceeds in high yield and affords only the ( " E " )-isomer of the corresponding aldimines and ketimines or N-Sulfinyl imines.
• A general approach to the formation of sulfinyl chlorides, RS ( O ) Cl, is by reaction of the corresponding thiol with sulfuryl chloride,, but in some cases the sulfenyl chloride results instead, as happens with 2, 2, 2-trifluoro-1, 1-diphenylethanethiol.
• A general approach to the formation of sulfinyl chlorides is by reaction of the corresponding thiol with sulfuryl chloride,; in cases where the sulfenyl chloride, RSCl, results instead, a trifluoroperacetic acid oxidation affords the desired product, as in the case of 2, 2, 2-trifluoro-1, 1-diphenylethanethiol:
• Treatment of methanesulfinyl chloride or ethane-1, 2-bis-sulfinyl chloride, ( prepared by oxidative chlorination of 1, 2-ethanedithiol, HSCH 2 CH 2 SH ), with a tertiary amine in the presence of the chiral glucose-derived secondary alcohol diacetone-D-glucose affords optically pure sulfinate esters by a process of Dynamic kinetic resolution.
• A general approach to the formation of sulfinyl chlorides, RS ( O ) Cl, is by reaction of the corresponding thiol with sulfuryl chloride,; in cases where the sulfenyl chloride, RSCl, results instead, a subsequent trifluoroperacetic acid oxidation affords the desired product, as in the case of 2, 2, 2-trifluoro-1, 1-diphenylethanethiol: