thorotrast การใช้

• Thorotrast exposure has also been associated with the development of angiosarcoma.
• About 2 to 10 million patients worldwide have been treated with Thorotrast.
• The risk of leukemia appears to be 20 times higher in Thorotrast patients.
• Due to the release of alpha particles, Thorotrast was found to be extremely carcinogenic.
• The cancers occur some years ( usually 20-30 ) after injection of Thorotrast.
• It has also been associated with individuals exposed to arsenic-containing insecticides and Thorotrast.
• It was sold under the name Thorotrast.
• The use of thorotrast was halted after scientists learned of its harmful effects to the liver.
• Autoradiography was then used by the Finsen Institute to investigate the effects of the radiocontrast agent thorotrast.
• There is a high over-incidence of various cancers in patients who have been treated with Thorotrast.
• Hemangiosarcomas are commonly associated with toxic exposure to thorium dioxide ( Thorotrast ), vinyl chloride, and arsenic.
• He also contributed to the development of Thorotrast for use in the procedure and contributed many lectures and papers on the subject.
• In the form of Thorotrast, a thorium dioxide suspension, it was used as contrast medium in early X-ray diagnostics.
• German patients exposed to Thorotrast had their median life-expectancy shortened by 14 years in comparison to a similar non-exposed control group.
• The risk of developing bile duct cancer ) in former Thorotrast patients has been measured to be well above 100 times the risk of the rest of the population.
• Historadiography has also been used to visualize staining of tissue, such as spinal cord samples with thorotrast, which contains thorium that is opaque to X-rays.
• Historically, contrast media was sometimes highly dangerous but these dangers were not well-understood during the development of the early types of contrast media, such as Thorotrast.
• Among other things, the scientists are studying the effects of thorotrast, a radioactive substance that at one time was injected into patients to aid in medical diagnoses of brain tissues.
• Radiologic contrast medium, has been linked to the development of cholangiocarcinoma as late as 30 40 years after exposure; Thorotrast was banned in the United States in the 1950s due to its carcinogenicity.
• Unfortunately, some elements chosen proved to be harmful  for example, thorium was once used as a contrast medium ( Thorotrast )  which turned out to be toxic, causing a very high incidence of cancer decades after use.