timolol การใช้

• Timolol helped 30 percent of blacks and 37 percent of non-blacks.
• Beta-blockers, such as timolol, work by decreasing aqueous formation.
• The combination of brinzolamide with timolol is marketed under the trade name Azarga.
• The drug is a combination of two chemicals : dorzolamide hydrochloride and timolol maleate.
• Neither brimonidine tartrate nor timolol maleate was mutagenic in in vitro and in vivo studies.
• Standard first-line therapy is timolol, an eyedrop that makes the eye produce less fluid, thus reducing pressure.
• The correct structure of Timolol includes a tertiary butylated nitrogen and the synthesis shows an iPr group instead of the tBu.
• Meta-analysis suggests that latanoprost is more effective than timolol in lowering IOP . However, it often causes iris pigmentation.
• A Cochrane Systematic Review compared the effect of timolol versus brimonidine in slowing the progression of open angle glaucoma in adult participants.
• A Cochrane Systematic Review compared the effect of brimonidine and timolol in slowing the progression of open angle glaucoma in adult participants.
• Several reports have demonstrated the efficacy of topical application of the beta-adrenergic antagonist timolol in the treatment of pediatric pyogenic granuloma.
• Reproduction and fertility studies in rats did not reveal any adverse effects on male or female fertility with brimonidine tartrate or timolol maleate.
• Travatan's maker studied 600 patients who took either Travatan, Xalatan or timolol, including some 50 black patients in each drug group.
• When symptoms are sufficiently troublesome to warrant treatment, the first medication choices are beta blockers such as propranolol or alternately, nadolol and timolol.
• Studies have shown bimatoprost to be more effective than timolol in reduction of intraocular pressure ( IOP ) and as least as effective as the prostaglandin analogs latanoprost and travoprost in reducing IOP.
• The trials gave the company precisely what it was looking for : proof that Xalatan, given once a day, lowered intraocular pressure as much as the gold standard of glaucoma treatment, timolol.
• In such cases, beta-2 stimulation with its consequent increase in humour production is highly contra-indicated, and conversely, a topical beta-2 antagonist such as timolol may be employed.
• Pharmacia is busy, too; it is already seeking FDA approval of a new product, a combination of Xalatan and timolol, the leading generic competitor, that could extend the life of the patent.
• But eye color difference may play yet another role : Some drugs bind to eye pigment differently than others, Chambers explained, saying doctors have long known that timolol works better in light-colored eyes than dark ones.
• Topical timolol maleate, a non-selective beta blocker available in a gel-forming solution approved for the treatment of glaucoma, has been increasingly recognized as a safe and effective off-label alternative for treatment of small hemangiomas.