tocainide การใช้

• In the blood tocainide is 10-20 % protein bound.
• The main metabolite is the glucuronidated tocainide carbamic acid.
• Tocainide is a lidocaine analog, that does not have significant 1st pass metabolism.
• These include above all amiodarone, as well as beta blockers, ACE inhibitors ( however, pulmonary toxicity of ACE inhibitors usually lasts only 3 4 months and then usually disappears by itself ), procainamide, quinidine, tocainide, and minoxidil.