tocolytic การใช้

• Sulindac is an effective tocolytic and may be used in the treatment of preterm labor.
• There is no need for chronic administration of tocolytic agents since postoperative uterine contractions are barely ever observed.
• It is used as an intravenous medication as a labour repressant ( tocolytic ) to halt premature labor.
• From the 1960s to the 1980s, alcohol was commonly used as a tocolytic, a method to stop preterm labor.
• A clinical trial ( Salim R " et al . ", 2012 ) compared tocolytic efficacy and tolerability of atosiban with that of nifedipine.
• In any case, 5?-DHP has nonetheless been shown to possess tocolytic effects in animals, and this may alternatively be mediated by activation of the PXR.
• Indometacin is an effective tocolytic agent, able to delay premature labor by reducing uterine contractions through inhibition of prostaglandin synthesis in the uterus and possibly through calcium channel blockade.
• A biochemist might examine, for instance, the influence of social and ecological conditions on the release of certain neurotransmitters and hormones, and the effects of such releases on behaviour, e . g . stress during birth has a tocolytic ( contraction-suppressing ) effect.
• The suppression of contractions is often only partial and tocolytics can only be relied on to delay birth for several days . Depending on the tocolytic used the mother or fetus may require monitoring, as for instance blood pressure monitoring when nifedipine is used as it reduces blood pressure.
• While the use of tocolytic agents or the development of preeclampsia ( toxemia of pregnancy ) and pregnancy-induced hypertension ( PIH ) may contribute to the worsening of heart failure, they do not cause PPCM; the majority of women have developed PPCM who neither received tocolytics nor had preeclampsia nor PIH.