xanthoma การใช้

• Still, it is often classified simply as a subtype of xanthoma.
• Clinical features are not well understood and there are no characteristic xanthomas.
• Xanthomas are one of types of skin lesions that may occur in this situation.
• Palmar crease xanthomas may also occur.
• Tendon xanthomas are associated with type II hyperlipidemia, chronic biliary tract obstruction, and primary biliary cirrhosis.
• Other typical symptoms are eruptive xanthomas ( in about 50 % of patients ), lipemia retinalis and hepatosplenomegaly.
• Familial dysbetalipoproteinemia causes larger, tuberous xanthomas; these are red or orange and occur on the elbows and knees.
• Juvenile variety xantogranuloma can be distinguished from xanthoma by the spread of the lesion and the lack of lipid abnormalities.
• Strictly, a xanthelasma is a distinct condition, only being called a xanthoma when becoming larger and nodular, assuming tumorous proportions.
• The symptoms are similar to pancreatitis secondary to other causes, although the presence of xanthomas or risk factors for hypertriglyceridemia may offer clues.
• Signs of familial dysbetaproteinemia include xanthoma striatum palmare ( orange or yellow discoloration of the palms ) and tuberoeruptive xanthomas over the elbows and knees.
• Signs of familial dysbetaproteinemia include xanthoma striatum palmare ( orange or yellow discoloration of the palms ) and tuberoeruptive xanthomas over the elbows and knees.
• Partial biliary diversion has been used to significantly reduce pruritus, jaundice, and xanthomas caused by poor bile flow in patients with bile duct paucity.
• A " xanthelasma " may instead be referred to as a " xanthoma " when becoming larger and nodular, assuming tumorous proportions.
• Eruptive xanthomas are 2 5 mm papules, often with a red ring around them, that occur in clusters on the skin of the trunk, buttocks and extremities.
• Physical examination findings can help a physician make the diagnosis of FH . Tendon xanthomas are seen in 20-40 % of individuals with FH and are pathognomonic for the condition.
• Some forms of primary hypertriglyceridemia can lead to specific symptoms : both familial chylomicronemia and primary mixed hyperlipidemia include skin symptoms ( eruptive xanthoma ), eye abnormalities ( lipemia retinalis ), hepatosplenomegaly ( enlargement of the liver and spleen ), and neurological symptoms.
• This may be sporadic ( due to dietary factors ), polygenic, or truly familial as a result of a mutation either in the LDL receptor gene on chromosome 19 ( 0.2 % of the population ) or the tendon xanthoma, xanthelasma, and premature cardiovascular disease.
• These individuals may present with a unique set of physical characteristics such as xanthelasmas ( yellow deposits of fat underneath the skin often presenting in the nasal portion of the eye ), tendon and tuberous xanthomas, arcus juvenilis ( the graying of the eye often characterized in older individuals ), arterial bruits, claudication, and of course atherosclerosis.
• Exercise should be promoted, as it can increase HDL . The overall prognosis for these individuals is in the worst-case scenario if uncontrolled and untreated individuals may die before the age of 20, but if one seeks a prudent diet with correct medical intervention, the individual may see an increased incidence of xanthomas with each decade, and Achilles tendinitis and accelerated atherosclerosis will occur.