alloantigen การใช้

• In direct alloantigen recognition, the involved dendritic cells are donor derived.
• Essentially, the MHC-peptide complex is a complex of autoantigen / alloantigen.
• In indirect alloantigen recognition, the dendritic cells ( APCs ) involved are recipient APCs.
• The main difference between indirect and direct alloantigen recognition stems from the origin of the macrophages ( type of APC ).
• Occasionally the'recombinant'A1-Cw7-B7 ( rare ), B7 becomes the alloantigen in a recipient with A1-Cw7-B8 ( common ).
• The use of the word alloantigen actually masks the fact that HLA are infrequently autoantigens in the donor, and therefore their function is not as antigens, but something else.