antitumour การใช้

• This immune response regulation also affects antitumour properties.
• From the 1950s the lichen product usnic acid was the object of most antitumour research.
• Target cell death without added complement after cooperation of 7s antitumour antibodies with non immune lymphocytes.
• This process is essential when APCs are not directly infected, triggering antiviral and antitumour immune responses.
• The antiulcer, laxative, antidiabetic, anti-inflammatory, immunomodulatory, antitumour and expectorant properties of liquorice have been investigated.
• It has been seen to show superior antitumour efficacy, which is purported to be linked to the activation of p53-independent apoptosis.
• One example of a successful use of this strategy is the screening for antitumour agents by the National Cancer Institute, started in the 1960s.
• "' Varacin "'is a bicyclic DNA, and varacin and synthetic analogues have been investigated for their antimicrobial and antitumour properties.
• These studies revealed some in vitro antitumour activity by substances identified in two common lichens " Peltigera leucophlebia " and " Collema flaccidum ".
• Modern research into possible medical applications have variously concluded that " A . auricula-judae " has antitumour, hypoglycemic, anticoagulant and cholesterol-lowering properties.
• 6 ) Enhanced Inhibition of Tumour Growth and Metastasis, and Induction of Antitumour Immunity by IL-2-IgG2b Fusion Protein-" Scandinavian Journal of Immunology"
• The antitumour effect of the vinca alkaloids ( e . g . vincristine ) was later shown to be due to their ability to inhibit microtubule polymerization alkaloys, and therefore cell division.
• In experiments on mice with tumour cells, it appeared to have antitumour effects when administered in combination with a preparation of " Propionibacterium acnes " in a 1994 Polish study.
• Cyanobacteria produce potent toxins, but they also produce helpful bioactive compounds, including substances with antitumour, antiviral, anticancer, antibiotic and antifungal activity, UV protectants and specific inhibitors of enzymes.
• ""'Micromonospora lupini " "'is an endophytic actinomycete notable for producing antitumour anthraquinones : lupinacidins A ( 1 ), B ( 2 ) and C . Its genome has been sequenced.
• The former, ?-conotoxin, is used to relieve severe and chronic pain, Other natural products derived from marine animals and under investigation as possible therapies include the antitumour agents discodermolide ( from the sponge " Discodermia dissoluta " ), eleutherobin ( from the coral " Erythropodium caribaeorum " ), and the bryostatins ( from the bryozoan " Bugula neritina " ).
• At MIT, Demain and his team  pioneered research on the elucidation and regulation of the biosynthetic pathways leading to penicillins and cephalosporins .  They did research into  peptide antibiotics and sporulation in B . subtilis; mycotoxins; new antibiotic discovery through mutational biosynthesis ( making idiotrophs ); cellulases and ethanologenic clostridia; vitamin B12; amino acids, organic acids and polymers; the immunosuppressant, rapamycin ( sirolimus ) and antitumour antibiotic, fumagillin; statins; pigments; vaccines ( developing media with non-animal components for clostridial vaccines ); and evaluating the impact of simulated microgravity on secondary metabolism 1 .  Demain's MIT research led to  a breakthrough discovery of a key enzyme in cephalosporin biosynthesis  deacetoxycephalosporin C synthetase ('expandase').