bufotenine การใช้
- In the case of tryptamine and serotonin these then become the dimethylated indolethylamines dimethyltryptamine ( DMT ) and bufotenine.
- In addition to bufotenine, " Bufo " venoms also contain digoxin-like cardiac glycosides, and ingestion of the venom can be fatal.
- After pushing doses to the morally admissible limit without producing visuals, Turner and Merlis conservatively concluded : We must reject bufotenine & as capable of producing the acute phase of Cohoba intoxication.
- Also stated in the book is this :'A character in the book is smoking synthetic toad-skins and inquires of the main character, Shadow, if he is aware that its possible to synthesize bufotenine now ?'
- Structurally, it is an analog of the naturally occurring neuro-active alkaloids dimethyltryptamine ( DMT ), bufotenine, and 5-methoxy-dimethyltryptamine, with an N-methyl sulfonamidomethyl-group at position C-5 on the indole ring.
- Presence of the hallucinogenic tryptamines 5-MeO-DMT, bufotenine and dimethyltryptamine, and supposedly the beta-carboline 6-MeO-harmane has been confirmed in " M . pruriens ", apparently the only thoroughly researched species thus far.
- Tests " in vitro " show 5-HO-DiPT to have high 5-HT 2A affinity and good selectivity over 5-HT 1A, while being more lipophilic than the related drug bufotenine ( 5-HO-DMT ), which produces mainly peripheral effects.