coumestrol การใช้

• Coumestrol is a phytoestrogen, mimicking the biological activity of estrogens.
• Coumestrol, an isoflavone coumarin derivative is the only coumestan in foods.
• Red clover contains coumestrol, a phytoestrogen.
• Coumestans, including coumestrol, a phytoestrogen, are found in a variety of plants.
• The chemical shape of coumestrol orients its two inhibit the activity of aromatase and 3?-hydroxysteroid dehydrogenase.
• In any case, coumestrol has estrogenic activity that is 30 to 100 times greater than that of isoflavones.
• Pinto beans have also been shown to contain the phytoestrogen coumestrol, which has a variety of possible health effects.
• "' Coumestrol "'is a natural organic compound in the class of phytochemicals known as coumestans.
• In plants which produce the phytoestrogen coumestrol, such as alfalfa, damage by aphids is linked with higher concentrations of coumestrol.
• In plants which produce the phytoestrogen coumestrol, such as alfalfa, damage by aphids is linked with higher concentrations of coumestrol.
• The highest concentrations of coumestrol are found in clover, Kala Chana, a type of chick pea, and Alfalfa sprouts.
• Coumestrol was first identified as a compound with estrogenic properties by E . M . Bickoff in ladino clover and alfalfa in 1957.
• Based on extrapolation from studies done on animals, the maximum tolerable daily intake of coumestrol for human beings has been estimated at 22 ?g per kg of body mass.
• Coumestrol has about the same binding affinity for the 17?-estradiol, although the estrogenic potency of coumestrol at both receptors is much less than that of 17?-estradiol.
• Coumestrol has about the same binding affinity for the 17?-estradiol, although the estrogenic potency of coumestrol at both receptors is much less than that of 17?-estradiol.
• A comparative study of the estrogenic properties of phytoestrogens found that both deoxymiroestrol and miroestrol were comparable in activity " in vitro " to other known phytoestrogens such as coumestrol as 17?-oestradiol agonists.
• Although, due to the variability of the human diet, the exact amount of coumestrol the average person consumes has not been calculated, studies of phytoestrogen intake suggest that most human diets result in a negligible intake of coumestrol relative to the maximum tolerable daily intake.
• Although, due to the variability of the human diet, the exact amount of coumestrol the average person consumes has not been calculated, studies of phytoestrogen intake suggest that most human diets result in a negligible intake of coumestrol relative to the maximum tolerable daily intake.
• Coumestrol binds to the ER? and ER? with similar affinity to that of estradiol ( 94 % and 185 % of the relative binding affinity of estradiol at the ER? and ER?, respectively ), although the estrogenic activity of coumestrol at both receptors is much less than that of estradiol.
• Coumestrol binds to the ER? and ER? with similar affinity to that of estradiol ( 94 % and 185 % of the relative binding affinity of estradiol at the ER? and ER?, respectively ), although the estrogenic activity of coumestrol at both receptors is much less than that of estradiol.