diosgenin การใช้

• Syntex chemists synthesized cortisone from diosgenin, a phytosteroid contained in Mexican yams.
• Its fruits contain diosgenin, a hormone precursor that presumably hinders the development of schistosomes.
• Expression Analysis of Steroid Pathway Genes Revealed Positive Correlation with Diosgenin Biosynthesis in Trillium govanianum.
• Diosgenin, a steroidal sapogenin, is reported from " S . menispermoidea ".
• It contains diosgenin, a possible estrogen mimic, and is used as a medicinal plant.
• Examples include digoxin, digitoxin, diosgenin, and guggulsterone, as well as phytosterols like ?-sitosterol.
• Diosgenin contained in fenugreek and wild yam affected maturation, but that wasn't enough evidence for this indication.
• Russell Marker, at Syntex, discovered a much cheaper and more convenient starting material, diosgenin from wild Mexican yams.
• He worked on a new synthesis of cortisone based on diosgenin, a steroid sapogenin derived from a Mexican wild yam.
• It is notable for its production of diosgenin, which is a precursor for the synthesis of hormones such as progesterone.
• He searched the woodlands from Canada to Mexico and focused on a sapogenin called diosgenin, because it required the fewest conversion steps.
• Some varieties of yams have been found to contain high levels of diosgenin, a chemical similar to estrogen, the female sex hormone.
• Later the Mexican barbasco trade focused instead on " Dioscorea composita " instead, as this variety has a higher diosgenin content.
• Wild yam grows here, as well, and its tuber is the source of diosgenin, a compound used to produce synthetic steroids and hormones.
• The sugar-free ( aglycone ), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products.
• The acopio owners knew more about the process and eventually invented ways of improving the diosgenin concentration in roots collected by adding different solvents to the tubers before shipping them to the beneficios.
• A steroidal saponin, diosgenin, is present in the flesh of the fruit and in the stone, and is a substance of interest as a primary compound for the production of pharmaceutical steroids.
• His conversion of diosgenin into progesterone by a four-step process now known as Marker degradation was an important step in mass production of all steroidal hormones, including cortisone and chemicals used in hormonal contraception.
• Diosgenin and hecogenin, which were commonly used in the West as precursors for steroid synthesis, were not available in East Germany, and for political and economic reasons, these substances could not be imported.