diphosphates การใช้

• Nucleotide exchange factors actively assist in the exchange of depleted nucleoside diphosphates for fresh nucleoside triphosphates.
• Beyond the diphosphates, sodium salts are known triphosphates, e . g . sodium triphosphate and tetraphospates.
• It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP-> NDP + Pi-> NMP + 2Pi.
• Phosphoanhydride bonds in ADP and ATP, or other nucleoside diphosphates and triphosphates, contain high amounts of energy which give them their vital role in all living organisms.
• In 1955, Marianne Grunberg-Manago and colleagues published a paper describing the enzyme polynucleotide phosphorylase, which cleaved a phosphate group from nucleotide diphosphates to catalyze their polymerization.
• Heating to higher temperatures in an inert atmosphere decomposes Pa ( PO 3 ) 4 into the diphosphate PaP 2 O 7, which is analogous to diphosphates of other actinides.
• "' Nucleotide exchange factor "'s ( "'NEF "'s ) are proteins that stimulate the exchange ( replacement ) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.
• Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions.
• Catalysis of ribonucleoside 5-diphosphates ( NDPs ) involves a reduction at the 2-carbon of ribose 5-phosphate to form the 2-deoxy derivative-reduced 2-deoxyribonucleoside 5-diphosphates ( dNDPs ).
• Catalysis of ribonucleoside 5-diphosphates ( NDPs ) involves a reduction at the 2-carbon of ribose 5-phosphate to form the 2-deoxy derivative-reduced 2-deoxyribonucleoside 5-diphosphates ( dNDPs ).
• The nucleoside diphosphate ( NDP ) kinases ( EC 2.7 . 4.6 ) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri-and diphosphates.