endocannabinoids การใช้

• Endocannabinoids are molecules that can relieve pain by modulating nociceptive neurons.
• Additionally, endocannabinoids play an important role in regulating various forms of synaptic plasticity.
• For example, researchers have linked endocannabinoids to addictive behaviors, memory and immune function.
• The mice lacked " receptor " structures that endocannabinoids activate in the brain.
• All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds.
• Endocannabinoids like anandamide are known to act as retrograde messengers, as is nitric oxide.
• It is thought that hypothalamic neurons tonically produce endocannabinoids that work to tightly regulate hunger.
• Evidence suggests that endocannabinoids may function as both neuromodulators and immunomodulators in the immune system.
• Researchers at Scripps Research Institute have described a novel pathway for the biosynthesis of endocannabinoids.
• It is unknown how endocannabinoids are created by the body, or precisely how they work.
• The amount of endocannabinoids produced is inversely correlated with the amount of leptin in the blood.
• It also blocks the body's own versions of cannabis, the so-called endocannabinoids.
• The endocannabinoids anandamide and noladin ether have also been shown to be neuroprotective against amyloid beta in vitro.
• Have endocannabinoids or their absence been implicated or ruled out as part of the mechanism of autism spectrum disorders?
• This research also studies DSIs, showing that DSIs interrupt metabotropic acetylcholine-initiated rhythm through the release of endocannabinoids.
• In the study, obese rats that were genetically modified to have low levels of leptin produced higher amounts of endocannabinoids.
• A 2004 study suggested that the endocannabinoids and their cannabinoid receptors play a major role during pre-and postnatal development.
• Endocannabinoids ( eCBs ) are one class of molecules that have been shown to direct pyramidal cell development and axonal pathfinding.
• For example, mice that were genetically engineered so they could not respond to endocannabinoids ate less and were thinner than normal.
• Additionally, anandamide and other endocannabinoids are found in the model organism " Drosophila melanogaster " ( fruit fly ).