ergotoxine การใช้

• Although, if the animal had been exposed to ergotoxine, the blood pressure decreased.
• Ergotinine, discovered in 1875, and ergotoxine ( 1906 ) were subsequently proven to be a mixture of several alkaloids.
• He proposed that the ergotoxine caused " selective paralysis of motor myoneural junctions " ( i . e . those tending to increase the blood pressure ) hence revealing that under normal conditions that there was a " mixed response ", including a mechanism that would relax smooth muscle and cause a fall in blood pressure.